PBX-7011 TFA is a derivative of camptothecin that exhibits anticancer activity. It functions by inhibiting the expression of cancer-related survival genes, specifically DDX5, Survivin, Mcl-1, and XIAP, in FaDu cells. Additionally, it degrades DDX5 proteins.
- Derivative of camptothecin.
- Inhibits expressions of cancer related survival genes DDX5, Survivin, Mcl-1, and XIAP in FaDu cells.
- Degrades DDX5 proteins.
- Exhibits anticancer activity.